Researchers Working on Tool to Determine Drug Risks During Pregnancy

Biomedical and chemical engineering Professor Zhen Ma and his Syracuse University research team have developed an in vitro 3D tissue model of a human heart based on human induced pluripotent stem cells (hiPSC). A model existing outside the body makes it possible to test drugs often prescribed during pregnancy and learn how they influence hiPSC growth, cardiac differentiation, and early heart formation in a fetus. Ma, in collaboration with a Syracuse University Falk College of Public Health professor and a professor from SUNY Upstate received funding for five years through an NIH Research Grant Award (RO1) to use the cardiac organoid model to improve traditional pharmaceutical screening. Read more here.