2020 NIH Shared Instrumentation for Animal Research (SIFAR) Grant Program

The Syracuse University Office of Research pleased to announce the launch of the NIH Shared Instrumentation for Animal Research (SIFAR) Grant Program Limited Submission competition. Click here to view the full competition information.

NIH Program Announcement: Link to NIH SIFAR Program Announcement
Number of Possible Internal Nominees: 1
Internal Submission Due Date: Thursday, April 2, 2020, 5:00 PM
Selection Notifications: Thursday, April 23, 2020
Sponsor Deadline (or submission window if NSF): Wednesday, June 1, 2020
Funding amount: One item of the requested instrumentation must cost at least $50,000. No instrument in a cluster can cost less than $20,000. There is no maximum price requirement; however, the maximum award is $750,000.

A Limited Submission is a funding opportunity for which the sponsor sets an institutional limit for the number of proposals it will accept. In order to participate, Syracuse University must organize to submit our most competitive proposal(s). This requires an internal competition.

Synopsis of the NIH SIFAR Program

The Shared Instrumentation for Animal Research (SIFAR) Grant Program invites groups of NIH-funded investigators engaged in biomedical research using animals to seek support for high-cost, state-of-the art, commercially available scientific instruments. All requested instruments must be used on a shared basis and enhance research that uses animals or related materials such as animal tissues, cells, or germplasm.

Applicants may request clusters of instruments configured as specialized integrated systems or as a series of instruments to support a specific thematic area of biomedical research using animals. An integrated instrumentation system is one in which components, when used in conjunction with one other, perform a function that no single component can provide. A series of instruments may support a specialized workflow or provide synergetic functionalities to advance a thematic area of research. Any instrument, requested as a part of a cluster or a series, must be commercially available.

Requests for single instruments are not appropriate for this FOA and, if submitted to this FOA, they will not be considered for funding. Single instrument requests are supported by the Shared Instrumentation Grant (SIG) Program or the High-End Instrumentation (HEI) Grant Program. Concurrent submissions to the SIFAR, SIG, and HEI Programs can be made only under conditions described in Section III.

All requests must be justified by the needs of NIH-funded projects and must demonstrate how the instruments will enhance the conduct of animal research and strengthen scientific outcomes. Priority will be given to specialized clusters of instruments and uniquely configured systems to support innovative and potentially transformative animal research.

To promote cost effectiveness, to encourage optimal sharing among individual investigators, research groups, and academic departments, and to foster a collaborative multidisciplinary environment, the requested instruments should be integrated in a core facility, whenever practical.

Foreign-made equipment is allowable.


  • The PD/PI chosen for this application should have documented (in the biographical sketch) technical expertise directly related to the requested instrumentation or scientific expertise in biomedical research using animals, must be affiliated with the applicant organization.
  • The PD/PI does not need to have an NIH research grant or any other research support but is expected to be an expert on the requested instrument.
  • The PD/PI may be a Core director or non-tenured faculty member of the applicant organization, must be affiliated with the applicant organization, and must be registered on eRA Commons.
  • Multiple PDs/PIs are not allowed under the S10 mechanism.
  • At least three Major Users who have substantial need for the instrument must be identified. Each of these Major Users must be a PD/PI on a distinct active NIH research award (i.e., a grant or a cooperative agreement) in an area of basic, translational, or clinical research.

Funding and award period

Applications will be accepted for commercially available instruments only. At least one item of the requested instrumentation must cost at least $50,000, after all applicable discounts. No instrument in a cluster can cost less than $20,000, after all applicable discounts. There is no upper limit on the cost of each instrument, but the maximum award is $750,000 of direct costs. Since the cost of the various instruments will vary, it is anticipated that the amount of the award will also vary. S10 awards do not allow indirect costs.Instruments must be for research purposes only.

Awards are made for one year only.

Application Materials

Applicants must submit a 4-page project description, a summary of Project Costs, biosketch for the PI, and confirmation of at least 3 Major Users with active NIH research awards. Full details of application requirements may be found on the Syracuse University Application Portal.

Limited Submission Selection Process:

Each team interested in submitting a proposal must submit a limited submission proposal by the stated deadline, using the procedure and format described in this section. If the number of proposals submitted exceeds the number that the University can submit to the NSF, peer review will be triggered. During review the proposals will be ranked in several categories, including:

  • The likelihood of receiving funding based on NIH merit review criteria;
  • The potential increase in research capacity that the equipment will provide to the institution in conjunction with consideration of University research priorities and needs;
  • The utility of the equipment to multiple users; AND
  • The strength of the operational and management plan (including planning for maintenance, user support, and usage reporting).

The PIs of projects selected to move forward with full proposals will be notified by email on or before Thursday, April 23, 2020. Per the sponsor restrictions, no more than one submission will be selected by Syracuse University.

At the discretion of the Office of Research, internal proposals submitted past the internal deadline will be considered for a full submission to the sponsor, on a case-by-case basis, if the addition of a proposal would not exceed our institutional limit.

Questions: Email LimitedSubmissions@syr.edu

Please note: Companion funding opportunities are available from NIH. These opportunities are not limited submissions.

PAR-20-114 S10 High-End Instrumentation (HEI) Grant Program (Clinical Trial Not Allowed)

PAR-20-113 S10 Shared Instrumentation Grant (SIG) Program (Clinical Trial Not Allowed)

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